This project has concluded.

Aresty Research Assistant
Advanced control of continuous pharmaceutical manufacturing pilot-plant
Project Summary
The industry 4.0 standard continuous pharmaceutical manufacturing (CM) integrated with real time monitoring, advanced process control (APC), and a novel data management system is highly desired to consistently produce the better quality product with less time and resources.
In this work, a bi-layer advanced control strategy will be developed and implemented into CM pilot-plant using industry standard real time monitoring sensors, data management tool and control platform. In first layer, the product (tablet) quality will be controlled in real time using advanced model predictive control (MPC) system while in second layer, the none-confirming products will be diverted in real time in waste to assure the final quality of qualified tablet lots. This bi-layer control strategy will assure the final product quality, and will improve the production efficiency.



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