"The organization of the cell's genome in three dimensions is fundamental to different cellular functions. The nucleus is divided into distinct chromosomal territories and each chromsome is segregated into active or repressed regions. While the utility of organizing the chormsome remains under investigation, it is known that multiple mechanisms orchestrate DNA organization. Crucially, Topologically Associating Domains (TADs) serve as key structural units, forming DNA loops that physically segregate (...)
Life Sciences Alliance SURF
SAS - DLS - Cell Biology and Neuroscience
Cell & Molecular Biology, Genomics , Life Sciences
Self-limiting electrospray deposition (SLED) has been developed by our group for the conformal coating of macromolecules onto complex 2D and 3D surfaces. We have recently demonstrated two capabilities that have opened up a new potential application area: (1) SLED from 99.8% water solutions and (2) multilayer SLED with controlled layer thickness. We propose to use these capabilities to deposit bilayer coatings of protein + excipient coated by a biocompatible polymer shell. Based on the thickness (...)
Life Sciences Alliance SURF
Engn - Mechanical & Aerospace Engineering
Life Sciences
This project aims to perform a literature review on control theory applications to LLMs and develop preliminary implementations of relevant control methods to potentially influence their behavior.
RAD Collaboratory SURF
Engn - Mechanical & Aerospace Engineering
Artificial Intelligence
The Tutwiler laboratory is focused on studying the structure-function relationship of blood clot formation, with a particular focus on the mechanics and enzymatic function. Immune cells and inflammation play a unique role in the activation and regulation of blood clotting and warrant further examination. We are particularly interested in examining the role of inflammation due to its pathophysiolgical relevance to traumatic injury, cancer, spinal cord injury etc. We aim to explore the mechanisms (...)
Life Sciences Alliance SURF
Engn - Biomedical Engineering
Biomedical Engineering, Chemical Engineering, Structural (...)
"Artificial Intelligence (AI) is rapidly transforming education by offering new ways to support student learning and success. This project will examine how AI tools can enhance academic performance, engagement, and overall well-being in undergraduate Economics and Business courses. Students will work with me to analyze how AI-based tools, such as personalized learning platforms, AI chatbots, and feedback systems—can create individualized learning pathways. These tools help educators deliver timely (...)
RAD Collaboratory SURF
SEBS - Agricultural & Resource Management Agents
Data Science
